Venous disease, which impacts more than 30 million Americans, refers to conditions related to or caused by veins that become diseased or abnormal. The disease occurs when vein walls become weak, damaged, stretched or injured and veins stop working normally, causing the blood to begin to flow backward as the muscles relax. This creates unusually high pressure in the veins.
Venous disease includes conditions such as Varicose veins and Chronic Venous Insufficiency (CVI). If left untreated, varicose veins can progress to CVI, which is a more serious form of venous disease. Signs and symptoms of CVI can worsen over time and include ankle swelling, fatigue, restlessness and pain of the legs, skin changes and ulcers.